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Open Access Highly Accessed Research

Epidemiology of urinary tract infections and antibiotics sensitivity among pregnant women at Khartoum North Hospital

Hamdan Z Hamdan1, Abdel Haliem M Ziad2, Salah K Ali3 and Ishag Adam4*

Author Affiliations

1 Faculty of Medicine, Al-Neelain University, Khartoum, Sudan

2 Khartoum North Hospital, Khartoum, Sudan

3 National health laboratory, Khartoum, Sudan

4 Faculty of Medicine, University of Khartoum, Khartoum, Sudan

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Annals of Clinical Microbiology and Antimicrobials 2011, 10:2  doi:10.1186/1476-0711-10-2

Published: 18 January 2011

Abstract

Background

Urinary tract infections (UTI) can lead to poor maternal and perinatal outcomes. Investigating epidemiology of UTI and antibiotics sensitivity among pregnant women is fundamental for care-givers and health planners.

Methods

A cross sectional study has been conducted at Khartoum north teaching hospital Antenatal Care Clinic between February-June 2010, to investigate epidemiology of UTI and antibiotics resistance among pregnant women. Structured questionnaires were used to gather data from pregnant women. UTI was diagnosed using mid stream urine culture on standard culture media

Results

Out of 235 pregnant women included, 66 (28.0%) were symptomatic and 169 (71.9%) asymptomatic. the prevalence of bacteriuria among symptomatic and asymptomatic pregnant women were (12.1%), and (14.7%) respectively, with no significant difference between the two groups (P = 0.596), and the overall prevalence of UTI was (14.0%). In multivariate analyses, age, gestational age, parity, and history of UTI in index pregnancy were not associated with bacteriuria. Escherichia coli (42.4%) and S. aureus (39.3%) were the commonest isolated bacteria. Four, 2, 2, 3, 4, 2 and 0 out of 14 E. coli isolates, showed resistance to amoxicillin, naladixic acid, nitrofurantoin, ciprofloxacin, co-trimoxazole, amoxicillin/clavulanate and norfloxacin, respectively

Conclusion

Escherichia coli were the most prevalent causative organisms and showing multi drug resistance pattern, asymptomatic bacteriuria is more prevalent than symptomatic among pregnant women. Urine culture for screening and diagnosis purpose for all pregnant is recommended.