Peritoneal tuberculosis and granulomatous hepatitis secondary to treatment of bladder cancer with Bacillus Calmette-Guérin

doi:10.1186/1476-0711-8-12

Annals of Clinical Microbiology and Antimicrobials

Volume 8

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Soylu A
Ince AT
Polat H
Yasar N
Ciltas A
Ozkara S
Tasci AI

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Soylu A
Ince AT
Polat H
Yasar N
Ciltas A
Ozkara S
Tasci AI
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Case report

Peritoneal tuberculosis and granulomatous hepatitis secondary to treatment of bladder cancer with Bacillus Calmette-Guérin

Aliye Soylu¹ , Ali T Ince² , Hakan Polat³ , Nurgul Yasar⁴ , Aydin Ciltas⁴ , Selvinaz Ozkara⁵ and Ali I Tasci³

¹Department of Gastroenterology, Bakirkoy Training and Research Hospital, Istanbul, Turkey

²Department of Gastroenterology, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey

³Department of Urology, Bakirkoy Training and Research Hospital, Istanbul, Turkey

⁴Department of Internal Medicine, Bakirkoy Training and Research Hospital, Istanbul, Turkey

⁵Department of Pathology, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey

author email corresponding author email

Annals of Clinical Microbiology and Antimicrobials 2009, 8:12doi:10.1186/1476-0711-8-12


Published:	15 April 2009

Abstract

Intravesical administration of Bacillus Calmette-Guérin is used as a treatment method in superficial bladder cancer. While it is generally well tolerated, serious side effects may develop. Granulomatous hepatitis cases have been previously reported; however, only one case with tuberculous peritonitis exists in the current literature. We hereby present two cases, one of which is the second tubercular peritonitis case following Bacillus Calmette-Guérin treatment to be reported, and the other a case with granulomatous hepatitis. Complete cure was achieved in both cases with specific therapy. In the patient who developed peritonitis, intravesical Bacillus Calmette-Guérin therapy was recommenced after antituberculosis treatment, and completed without further complications.