  Case reportStenotrophomonas maltophilia resistant to trimethoprim – sulfamethoxazole: an increasing problemAsma Marzouq Al-Jasser  MBBS, King Saud University Fellowship of Pathology (Microbiology), Jordanian Board (Microbiology & Immunology), Certification Board in Infection Control and Epidemiology(CIC), Consultant Microbiologist, Department of Microbiology. Armed Forces Hospital, Box X-966, P.O. Box 7897. Riyadh – 11159, Saudi Arabia  author email corresponding author email
Annals of Clinical Microbiology and Antimicrobials 2006,
5:23doi:10.1186/1476-0711-5-23
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18 September 2006 |
Abstract
Stenotrophomonas maltophilia (S. maltophilia) has recently emerged as an important nosocomial pathogen. Treatment of invasive infections caused by this organism is difficult as the bacterium is frequently resistant to a wide range of commonly used antimicrobials. Trimethoprim-sulfamethoxazole (TMP – SXT) is recommended as the agent of choice for the treatment of S. maltophilia infections. However, the development of resistance to this antibiotic represents a real challenge to laboratorians and clinicians.
This letter describes the first isolation of S. maltophilia resistant to TMP – SXT from two patients treated at Riyadh Armed Forces Hospital which is a major tertiary hospital in Saudi Arabia. | 
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