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Open Access Highly Accessed Research

Sensitivity pattern among bacterial isolates in neonatal septicaemia in port Harcourt

Boma A West1 and Oliemen Peterside2*

Author Affiliations

1 Department of Paediatrics and Child Health, Braithewaite Memorial Specialist Hospital, Port Harcourt, Rivers State, Nigeria

2 Department of Paediatrics and Child Health, Niger Delta University Teaching Hospital, Okolobiri, Bayelsa State, Nigeria

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Annals of Clinical Microbiology and Antimicrobials 2012, 11:7  doi:10.1186/1476-0711-11-7

Published: 26 March 2012

Abstract

Background

The organisms responsible for neonatal sepsis vary across geographical boundaries and with the time of illness thus periodic bacteriologic surveillance is a neccessity. The present study was therefore carried out to determine the common bacterial pathogens in Port Harcourt and their sensitivity pattern.

Methods

Four hundred and six neonates were prospectively screened for sepsis over a 6 month period. Sensitivity of the bacterial isolates to different antibiotics was determined using Kirby-Bauer diffusion method.

Results

Gram negative organisms predominated (75.1%) with Klebsiella pneumonia (58.2%) being the commonest. The quinolones were the most sensitive antibiotics to the commonly isolated organisms.

Conclusion

Klebsiella pneumonia is the commonest organism responsible for neonatal sepsis in Port Harcourt. There is an overall decline in the antibiotic susceptibility to the commonly isolated bacterial pathogens.

Keywords:
Neonatal sepsis; Bacteria; Antibiotics; Port Harcourt