Table 1

PCR-results with a total of 380 tissue samples obtained from non-infected (control) and N. caninum-infected calves without and with ponazuril therapy (1T = medication for one day; 6T = medication for 6 consecutive days). Bold numbers indicate the number of positive samples per total number of samples analyzed; – means that no sample was PCR-positive. Infected animals without therapy were euthanized on day 45 p.i. (nos. 1–3) and 90 p.i. (nos. 4–6)


without infection
infection, without therapy
infection, with therapy

() = number of calves tested
without therapy (2)
with therapy_6T (2)
no.1 (1)
no.2 (1)
no.3 (1)
no.4 (1)
no.5 (1)
no.6 (1)
with therapy_1T (5)
with therapy_6T (4)

brain
- / 20
- / 20
- / 10
2 / 10
- / 10
- / 10
1 / 10
- / 10
- /50
- /40
heart
- / 6
- / 6
- / 3
- / 3
1 / 3
- / 3
- / 3
- / 3
- /15
- /12
muscles*
- / 6
- / 6
- / 3
1 / 3
- / 3
- / 3
1 / 3
- / 3
- /15
- /12
liver
- / 8
- / 8
- / 4
- / 4
- / 4
- / 4
- / 4
- / 4
- /20
- /16

*muscles: per animal, one sample from the M. masseter, one from the diaphragma and one from the tongue, respectively.

Kritzner et al. Annals of Clinical Microbiology and Antimicrobials 2002 1:4   doi:10.1186/1476-0711-1-4

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